The combined action of CTCF and its testis-specific paralog BORIS is essential for spermatogenesis
Samuel Rivero-Hinojosa, Elena M. Pugacheva, Sungyun Kang, Claudia Fabiola Méndez-Catalá, Alexander L. Kovalchuk, Alexander V. Strunnikov, Dmitri I. Loukinov, Jeannie T. Lee, Victor V. Lobanenkov
The paper shows that CTCF and BORIS work together in spermatogenesis, with their combined loss causing infertility due to defective meiosis and gene expression.
Nature Communications · Jun 22, 2021Peer-reviewedGenomics