Author

Louise T. Dalgaard

Roskilde UniversityORCID 0000-0002-3598-2775Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Anandwardhan A. HardikariD· 2 shared Charlotte X. DongiD· 2 shared Mugdha V. JoglekariD· 2 shared Wayne John HawthorneiD· 2 shared Wilson K. M. WongiD· 2 shared Yi Vee ChewiD· 2 shared Adwait Bhave· 1 shared Andrew G. ElefantyiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersGenetics

Anandwardhan A. HardikarORCID

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2 papers

Recent·Most cited

Machine learning algorithms in big data analyses identify determinants of insulin gene transcription

Wilson K. M. Wong, Vinod Thorat, Mugdha V. Joglekar, Charlotte X. Dong, Hugo Lee, Yi Vee Chew, Adwait Bhave, Wayne J. Hawthorne, Feyza Engin, Aniruddha Pant, Louise T. Dalgaard, Sharda Bapat, Anandwardhan A. Hardikar

The paper compares 10 machine learning workflows to identify genes associated with insulin transcript presence in human pancreatic single-cell transcriptomes, finding Random Forest to be highly predictive.

bioRxiv · Mar 27, 2021 · PreprintGenetics

A pro-endocrine pancreatic transcriptional program established during development is retained in human gallbladder epithelial cells

Mugdha V. Joglekar, Subhshri Sahu, Wilson K. M. Wong, Sarang N. Satoor, Charlotte X. Dong, Ryan J. Farr, Michael D. Williams, Prapti Pandya, Gaurang Jhala, Sundy N.Y. Yang, Yi Vee Chew, Nicola A. Hetherington, Dhan Thiruchevlam, Mitnala Sasikala, Guduru Venkat Rao, , Anandwardhan A. Hardikar

The paper shows human gallbladder epithelial cells retain a pro-endocrine pancreatic transcriptional program, enabling insulin production and immune protection in type 1 diabetes.

bioRxiv · Mar 2, 2021 · PreprintDevelopmental Biology