Author

Fredrik W. Sadler

University of MinnesotaORCID 0000-0002-3627-1940Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Elizaveta MukhalevaiD· 1 shared Nagarajan VaidehiiD· 1 shared Ning MaiD· 1 shared Sivaraj SivaramakrishnaniD· 1 shared Tianyi YangiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBiophysics

Elizaveta MukhalevaORCID

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1 paper

Recent·Most cited

BiophysicsiSciencePeer-reviewedMay 22, 2024

Cellular Lipids Regulate the Conformational Ensembles of the Disordered Intracellular Loop 3 in beta-2 Adrenergic Receptor

Elizaveta Mukhaleva, Tianyi Yang, Fredrik W. Sadler…·Nagarajan Vaidehi

This study shows that lipids like PIP2 and GM3 modulate the conformation of ICL3 in beta-2AR, affecting G protein coupling through membrane tilting and allosteric effects.

10 citations

proteomicsexperimental assay

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