Author

Guolun Wang

Cincinnati Children's Hospital Medical CenterORCID 0000-0002-3632-4061Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:graph neural network· 1

Frequent Co-Authors

Jichao CheniD· 2 shared Bingqiang WeniD· 1 shared Enhong LiiD· 1 shared Kamryn N. Gerner-MauroiD· 1 shared Kyungtae KangiD· 1 shared Lisandra Vila EllisiD· 1 shared Mingon KangiD· 1 shared Olena A. Kolesnichenko· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBioinformatics

Jichao ChenORCID

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3 papers

Recent·Most cited

Multi-modal Graph Integration for Biologically Interpretable Domain Identification Using Spatial Transcriptomics

S.J. Lee, Guolun Wang, Kyungtae Kang, Jichao Chen, Mingon Kang

This study introduces BIGraph-ST, a method that integrates pathway activity and histological features to improve spatial domain identification in spatial transcriptomics, showing better performance in cancer tissues.

bioRxiv · Aug 5, 2026 · PreprintBioinformatics

Morphogenic, molecular, and cellular adaptations for unidirectional airflow in the chicken lung

Kamryn N. Gerner-Mauro, Lisandra Vila Ellis, Guolun Wang, Richa Nayak, Peter Y. Lwigale, Ross A. Poché, Jichao Chen

The paper identifies morphogenic, molecular, and cellular adaptations in the chicken lung that enable unidirectional airflow through developmental processes and a novel alveolar cell type.

Development · Apr 3, 2025Peer-reviewedDevelopmental Biology

In Vivo Generation of Bone Marrow from Embryonic Stem Cells in Interspecies Chimeras

Bingqiang Wen, Guolun Wang, Enhong Li, Olena A. Kolesnichenko, Zhaowei Tu, Senad Divanovic, Tanya V. Kalin, Vladimir V. Kalinichenko

This study generates functional bone marrow from mouse ESCs in rat embryos using blastocyst complementation, demonstrating the ability to produce all hematopoietic cell lineages.

eLife · Sep 30, 2022Peer-reviewedDevelopmental Biology