Senad Divanovic

This study shows ATF3 helps macrophages manage cholesterol during metabolic stress by balancing inflammation and sterol-responsive gene expression.

Anakinra reduced preterm labor and inflammation in a Rhesus macaque model of E. coli-induced intrauterine infection.

This study uses patient-derived colon organoids to identify lipid-related metabolic dysfunction in pediatric ulcerative colitis and shows that PPAR-α inhibition can alleviate metabolic and inflammatory features.

This study compares the effects of GalNAc-siRNA-mediated KHK knockdown and small molecule KHK inhibition on hepatic metabolism in mice on a high-fat diet, finding divergent impacts on lipid metabolism and glucose tolerance.

This study shows that fructose metabolism via KHK-C increases ER stress and modulates the hepatic transcriptome, contributing to NAFLD progression in both genetic and diet-induced models.

This study generates functional bone marrow from mouse ESCs in rat embryos using blastocyst complementation, demonstrating the ability to produce all hematopoietic cell lineages.