Kasia M. Bieszczad

Sound-evoked auditory neurophysiological signals are a window into prodromal functional differences in a preclinical model of Alzheimer's Disease

The paper identifies an auditory brainstem response (ABR) biomarker for Alzheimer's Disease risk in rats, showing genetic risk prediction and intervention effects.

Learning-induced neurobiological mechanisms enabled by RGFP966 enhance signal-in-noise responsivity in auditory cortex and behavior

This study shows that RGFP966 enhances auditory learning and improves signal detection in noise by modulating cortical plasticity and noise suppression.

Functional diversities within neurons and astrocytes in the adult rat auditory cortex revealed by single-nucleus RNA sequencing.

The paper uses snRNA-seq to identify diverse neuron and astrocyte subtypes in the adult rat auditory cortex, revealing functional diversity in these cell types.

Learning induces unique transcriptional landscapes in the auditory cortex

The paper identifies genome-wide gene expression changes in the auditory cortex of rats during learning, highlighting pathways involved in long-term auditory memory formation.

Pharmacological inhibition of an epigenetic regulator during the formation of extinction memory reveals sensory cortical and subcortical codes for the specificity of salient cues.

The paper shows that inhibiting HDAC3 enhances extinction memory specificity by altering cortical and subcortical sensory coding in rats.

Precise memory is predicted by learning-induced sensory system neurophysiological plasticity

The paper identifies neural substrates for sound-specific memory by linking individual differences in auditory neuroplasticity to memory precision in rodents.