Author

Vikram Venkappayya Holla

National Institute of Mental Health and NeurosciencesORCID 0000-0002-3634-2219Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 1 Research Focus:polygenic risk· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Nitish L. KambleiD· 3 shared Pramod Kumar PaliD· 3 shared Ravi YadaviD· 3 shared Akshayaa GaneshiD· 1 shared Albert SteziniD· 1 shared Andie Pinto· 1 shared B. K. Panda· 1 shared Banashree MondaliD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Nitish L. KambleORCID

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3 papers

Recent·Most cited

Genetic & Genomic Medicinenpj Parkinson s DiseasePeer-reviewedJul 6, 2026

Whole-genome sequencing of 197 cases with Parkinson's Disease reveals novel pathogenic variants in the Indian population

Hiba Ali, Banashree Mondal, Andie Pinto…·Shweta Ramdas

The paper performs whole-genome sequencing on Parkinson's Disease cases in India to identify novel pathogenic variants and quantify polygenic risk.

1 citation

humanwhole-genome sequencing

NeurosciencebioRxivPreprintJan 21, 2026

LRRK2 I1371V Impairs Astrocytic Glucose Metabolism and Triggers Multi-Organellar Dysfunction in PD

Roon Banerjee, Rashmi Santhoshkumar, Vikram Venkappayya Holla…·Indrani Datta

This study shows that the LRRK2-I1371V mutation impairs astrocytic glucose metabolism and causes multi-organellar dysfunction in Parkinson's disease.

1 citation

humanexperimental assay

Genetic & Genomic MedicinemedRxivPreprintNov 22, 2025

Intermediate repeat alleles at polyglutamine repeat loci in the Indian population

Meghana Janardhanan, Akshayaa Ganesh, Sowmya Devatha Venkatesh…·Meera Purushottam

The paper examines the prevalence of intermediate CAG repeat alleles in specific genes among different populations and identifies their association with neuromotor symptoms.

DOI 10.1101/2025.11.22.25340801