Yong Hou

PanVariants improves variant calling by integrating k-mer and mapping methods, reducing errors and outperforming existing tools for SNVs, indels, and SVs.

The paper shows that ONT reads corrected by NGS can achieve assembly quality comparable to HiFi-based methods, offering a cost-effective alternative for genome assembly.

The DNBelab C4 portable, negative-pressure microfluidic device performs high-throughput single-cell transcriptome profiling, resolving species-specific cells and tissue heterogeneity in murine lung and cerebral cortex comparably to existing platforms.