Cancer BiologybioRxivPreprint
Mutation profiling of KRAS and BRAF in primary tumors and circulating tumor cells of colorectal cancer patients using PNA-LNA molecular switch
Md. Sajedul Islam, Eliza Ranjit, Sharmin Aktar…·Alfred King-yin Lam
This study uses the PNA-LNA molecular switch to detect KRAS and BRAF mutations in CRC tumors and CTCs, finding significant correlations between KRAS mutations in CTCs and clinicopathological features.
DOI 10.1101/2025.06.01.657284