Abul Bashar Mir Md. Khademul Islam

Medium-Chain Fatty Acid exposure in non-transformed mammary glands leads to pro-tumorigenic alterations associated with aging

This study shows that medium-chain fatty acid exposure in non-transformed mammary glands induces aging-like changes linked to breast cancer risk.

The binding sites of E2F transcription factor in Drosophila metabolic genes are functionally distinct

This study shows that E2F binding to the metabolic gene Pgk affects glycolytic flux, mitochondrial morphology, and lifespan in Drosophila.

SARS-CoV-2 mutations altering regulatory properties: deciphering host's and virus's perspectives

This study examines how SARS-CoV-2 mutations affect host miRNA binding and viral IRES structure, revealing potential impacts on immune pathways and viral function.

SARS-CoV-2 proteins exploit host's genetic and epigenetic mediators for the annexation of key host signaling pathways that confers its immune evasion and disease pathophysiology

This study identifies how SARS-CoV-2 proteins interact with host signaling pathways and epigenetic factors to evade immune responses and contribute to disease pathophysiology.

Viral miRNAs Confer Survival in Host Cells by Targeting Apoptosis Related Host Genes

The paper identifies that viral miRNAs target host apoptosis-related genes to suppress cell death, enhancing viral survival.

Lung biopsy cells transcriptional landscape from COVID-19 patient stratified lung injury in SARS-CoV-2 infection through impaired pulmonary surfactant metabolism

This study analyzes RNA-seq data from lung biopsy cells of COVID-19 patients to identify molecular mechanisms underlying lung injury, highlighting impaired surfactant metabolism and mitochondrial dysfunction.

Ancestral function of Inhibitors-of-kappaB regulates Caenorhabditis elegans development

This study identifies a role for C. elegans I{kappa}B homologs in chromatin regulation, showing they bind histones, Polycomb proteins, and alter chromatin marks, suggesting ancestral I{kappa}B functions in development.

Perversely expressed long noncoding RNAs can alter host response and viral proliferation in SARS-CoV-2 infection

The paper identifies 21 differentially expressed lncRNAs in SARS-CoV-2 infection that interact with host genes and microRNAs, influencing viral proliferation and immune response.

A single-cell transcriptome atlas of the adult muscle precursors uncovers early events in fiber-type divergence in Drosophila

The paper constructs a single-cell RNA-seq atlas of Drosophila muscle precursors to identify transcriptional signatures and a novel gene involved in muscle divergence.

Host transcriptional responses and SARS-CoV-2 isolates from the nasopharyngeal samples of Bangladeshi COVID-19 patients

This study analyzes transcriptomic profiles and SARS-CoV-2 isolates from Bangladeshi COVID-19 patients, revealing unique mutations and immune responses in nasopharyngeal samples compared to lung cells.

Epigenetic regulator miRNA pattern differences among SARS-CoV, SARS-CoV-2 and SARS-CoV-2 world-wide isolates delineated the mystery behind the epic pathogenicity and distinct clinical characteristics of pandemic COVID-19

The paper identifies miRNA pattern differences between SARS-CoV, SARS-CoV-2, and global SARS-CoV-2 isolates, linking them to pathogenicity and clinical outcomes.