Cancer BiologybioRxivPreprint
Adaptive replication origin activation alters chromatin dynamics and stability in cancer cells
Alejandro Pérez‐Venteo, Fernando Unzueta, Sònia Feu…·Neus Agell
This study shows colorectal cancer cells activate new replication origins after stress, leading to chromatin instability and increased tumour heterogeneity.
DOI 10.1101/2024.12.03.626323