Vladimir V. Egorov

Spontaneous formation of different forms of alpha-synuclein fibrils from a recombinant protein

This study shows that recombinant alpha-synuclein can form different fibril types under the same conditions, and these fibrils can act as seeds to produce similar fibrils.

Stick of Sticks: Structural Features of the Amyloidogenic Peptide-DNA Complex

This study investigates how an amyloidogenic peptide binds to DNA, showing its structural interactions and effects on DNA function.

Mangiferin As A Potential Inhibitor Of Transthyretin Fibrillogenesis

The paper predicts and validates that mangiferin inhibits transthyretin fibrillogenesis using in silico docking and in vitro assays.

Peptide from NSP7 is able to form amyloid-like fibrils: artifact or challenge to drug design?

The paper analyzes the primary structure of the NSP7 protein to identify potential amyloidogenic determinants and shows that synthesized peptides can form amyloid-like fibrils in vitro.

Old Dog, New Tricks: Influenza A Virus NS1 and In Vitro Fibrillogenesis

This study shows that influenza A NS1 protein can form amyloid-like fibrils in vitro, with structural changes detected by proteolysis and mass spectrometry.