Alexander G. Foote

Differential Enhancer Activity and FOXF1 Levels Contribute to Higher Inflammatory Gene Expression of Fetal/Neonatal Versus Adult Fibroblasts in IR-induced Senescence

The paper shows that fetal/neonatal fibroblasts show higher inflammatory gene expression than adult fibroblasts in IR-induced senescence due to differences in enhancer activity and FOXF1 levels.

A non-canonical role of Myc in programming basal cells as sentinels of upper airway immunity during influenza infection

This study identifies a non-canonical role of Myc in basal cells during influenza infection, showing its necessity for mucosal restoration and recruitment of CD8+ NKT cells.

A Single-Cell Atlas of the Upper Respiratory Epithelium Reveals Heterogeneity in Cell Types and Patterning Strategies

This paper presents a single-cell atlas of the mouse upper respiratory epithelium, identifying 17 cell types organized into three spatial compartments and revealing distinct transcriptional programs.