Author

Zhangfei Shen

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research InstituteORCID 0000-0002-3707-2265Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Assay:proteomics· 1

Frequent Co-Authors

Tian‐Min FuiD· 2 shared Anthony D. RishiD· 1 shared Chen WangiD· 1 shared Elizabeth FosuahiD· 1 shared Ila A. MaratheiD· 1 shared Kotaro NakanishiiD· 1 shared Vicki Hopper WysockiiD· 1 shared Xiaoyuan YangiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersBiochemistry

Tian‐Min FuORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Topological rearrangements activate the HerA-DUF anti-phage defense system

Anthony D. Rish, Elizabeth Fosuah, Zhangfei Shen, Ila A. Marathe, Vicki Hopper Wysocki, Tian‐Min Fu

The paper identifies topological rearrangements in the HerA-DUF complex that activate the anti-phage defense system, challenging the idea that oligomerization alone is sufficient for immune signaling.

Molecular Cell · Oct 24, 2024Peer-reviewedBiochemistry

DdmDE eliminates plasmid invasion by DNA-guided DNA targeting

Xiaoyuan Yang, Zhangfei Shen, Chen Wang, Kotaro Nakanishi, Tian‐Min Fu

This study elucidates the mechanism of the DdmDE system in eliminating plasmids through DNA-guided targeting and cleavage.

Cell · Aug 22, 2024Peer-reviewedBiophysics