Author

Hyungtai Sim

Seoul National UniversityORCID 0000-0002-3719-4190Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Hyungtai Sim1 paper · Yonsei University

Biology Disciplines

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Genomics· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Murim ChoiiD· 3 shared Geun‐Ho Park· 2 shared Se‐Hoon LeeiD· 2 shared Woong‐Yang ParkiD· 2 shared Geum‐Sook HwangiD· 1 shared Hee‐Hoon KimiD· 1 shared Ho KimiD· 1 shared Hyo Jung KimiD· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersGenomics

Murim ChoiORCID

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3 papers

Recent·Most cited

GenomicseLifePeer-reviewedNov 20, 2024

Increased inflammatory signature in myeloid cells of non-small cell lung cancer patients with high clonal hematopoiesis burden

Hyungtai Sim, Hyun Jung Park, Geun‐Ho Park…·Murim Choi

The paper examines the relationship between clonal hematopoiesis burden and immune response in NSCLC patients, finding higher CHIP prevalence in cancer patients and inflammatory pathway enrichment in myeloid cells with severe CHIP.

1 citation

humanbulk RNA-seq

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GenomicsbioRxivPreprintSep 16, 2024

Systemic CD8+ T cell effector signature predicts prognosis of lung cancer immunotherapy

Hyungtai Sim, Geun‐Ho Park, Woong‐Yang Park…·Murim Choi

The paper identifies a CD8+ T cell effector signature linked to lung cancer immunotherapy prognosis using single-cell RNA sequencing and eQTL analysis.

DOI 10.1101/2024.09.16.613381

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GeneticsJournal of HepatologyPeer-reviewedApr 20, 2021

Disease-specific eQTL screening reveals an anti-fibrotic effect of AGXT2 in nonalcoholic fatty liver disease

Taekyeong Yoo, Sae Kyung Joo, Hyo Jung Kim…·Murim Choi

The paper identifies AGXT2 as a gene with an anti-fibrotic effect in NAFLD through eQTL screening and functional validation.

57 citationstop 1%

humanbulk RNA-seq

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