ImmunologyeLifePeer-reviewed
An IL-21R STAT hypomorph circumvents functional redundancy in germinal center responses
Christoph Jandl, Joanna Warren, Samantha J. Owens…·Cecile King
This study identifies an IL-21R hypomorph mutation that specifically impairs STAT1 activation, revealing a nonredundant role for IL-21 in Tfh cell differentiation.
DOI 10.7554/elife.109834.3