STAT3 regulates the generation of astroglia inhuman brain organoids with high mTORC1 activity
Bipan Kumar Deb, Thomas L. Li, John D. Blair, Dirk F. Hockemeyer, Helen S. Bateup
The paper shows that STAT3, downstream of mTORC1, regulates astroglia generation in human brain organoids, but mTORC1 is not required for cytokine-induced STAT3 activation.
bioRxiv · Dec 21, 2023 · PreprintNeuroscience