Author

Thomas L. Li

University of California, BerkeleyORCID 0000-0002-8656-0679Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:electronic health records· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Helen S. BateupiD· 3 shared Bianxiao CuiiD· 2 shared Csaba ForróiD· 2 shared Dirk F. HockemeyeriD· 2 shared John D. Blair· 2 shared Sergiu P. PașcaiD· 2 shared Xiao YangiD· 2 shared Atehsa SahaguniD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersNeuroscience

Helen S. BateupORCID

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5 papers

Recent·Most cited

Gastrin-releasing peptide signaling in the nucleus accumbens medial shell regulates neuronal excitability and motivation

Erin E. Aisenberg, Thomas L. Li, Hongli Wang, Atehsa Sahagun, Emilie M Tu, Helen S. Bateup

This study identifies GRP/GRPR signaling in the nucleus accumbens medial shell as a regulator of neuronal excitability and motivation.

Nature Communications · Oct 21, 2025Peer-reviewedNeuroscience

mTORC1 activation drives astrocyte reactivity in cortical tubers and brain organoid models of TSC

Thomas L. Li, John D. Blair, Taesun Yoo, Gerald Arthur Grant, Dirk F. Hockemeyer, Brenda E. Porter, Helen S. Bateup

This study shows that mTORC1 activation in astrocytes drives reactivity in cortical tubers and brain organoids, linking it to TSC pathology.

bioRxiv · Feb 28, 2025 · PreprintNeuroscience

Kirigami electronics for long-term electrophysiological recording of human neural organoids and assembloids

Xiao Yang, Csaba Forró, Thomas L. Li, Yuki Miura, Tomasz J. Zaluska, Ching‐Ting Tsai, Sabina Kanton, James P. McQueen, Xiaoyu Chen, Valentina Mollo, Francesca Santoro, Sergiu P. Pașca, Bianxiao Cui

This paper introduces kirigami electronics for long-term, minimally-invasive electrophysiological recording of human neural organoids and assembloids in suspension.

Nature Biotechnology · Jan 22, 2024Peer-reviewedNeuroscience

STAT3 regulates the generation of astroglia inhuman brain organoids with high mTORC1 activity

Bipan Kumar Deb, Thomas L. Li, John D. Blair, Dirk F. Hockemeyer, Helen S. Bateup

The paper shows that STAT3, downstream of mTORC1, regulates astroglia generation in human brain organoids, but mTORC1 is not required for cytokine-induced STAT3 activation.

bioRxiv · Dec 21, 2023 · PreprintNeuroscience

Stretchable mesh microelectronics for the biointegration and stimulation of neural organoids

Thomas L. Li, Yuxin Liu, Csaba Forró, Xiao Yang, Levent Beker, Zhenan Bao, Bianxiao Cui, Sergiu P. Pașca

This paper introduces a stretchable mesh electrode system for long-term electrical interfacing with human cortical organoids, demonstrating stable performance and successful integration with neural tissue.

bioRxiv · Jun 10, 2022Neuroscience