Author

Harrison M. McAdams

University of PennsylvaniaORCID 0000-0002-3752-8939Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Assay:imaging· 2 Approach:statistical model· 2 Assay:electronic health records· 1 Approach:experimental assay· 1

Frequent Co-Authors

Aleksandra IgdalovaiD· 3 shared David H. BrainardiD· 3 shared Geoffrey K. AguirreiD· 3 shared Brett L. CucchiaraiD· 2 shared Edda Briana HaggertyiD· 2 shared Eric A. KaiseriD· 2 shared Manuel SpitschaniD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 18 mutual co-author links

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3 shared papersNeuroscience

Aleksandra IgdalovaORCID

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3 papers

Recent·Most cited

Enhanced reflexive eye closure is mediated by ipRGC signals and is specific to migraine with visual aura

Eric A. Kaiser, Harrison M. McAdams, Aleksandra Igdalova, Edda Briana Haggerty, Brett L. Cucchiara, David H. Brainard, Geoffrey K. Aguirre

The paper assesses the role of ipRGCs and cones in reflexive eye closure as a measure of photophobia in migraine, finding enhanced responses in MwA compared to other groups.

Neurology · Sep 7, 2021Peer-reviewedNeuroscience

Selective amplification of ipRGC signals accounts for interictal photophobia in migraine

Harrison M. McAdams, Eric A. Kaiser, Aleksandra Igdalova, Edda Briana Haggerty, Brett L. Cucchiara, David H. Brainard, Geoffrey K. Aguirre

This study investigates how melanopsin and cone signals contribute to photophobia in migraine and finds that migraineurs amplify ipRGC signals specifically for discomfort, not pupil responses.

Proceedings of the National Academy of Sciences · Jul 6, 2020Peer-reviewedNeuroscience

Pulses of melanopsin-directed contrast produce highly reliable pupil responses that are insensitive to a change in background radiance

Harrison M. McAdams, Aleksandra Igdalova, Manuel Spitschan, David H. Brainard, Geoffrey K. Aguirre

This study measures pupil responses to melanopsin-directed contrast pulses and finds they are reliable and insensitive to background radiance changes.

Investigative Ophthalmology & Visual Science · Nov 27, 2018Peer-reviewedNeuroscience