Michael J. Galko

ILP4 and InR regulate Paclitaxel-induced hypersensitivity differently in Drosophila larvae

This study investigates how ILP4 and InR regulate Paclitaxel-induced hypersensitivity in Drosophila larvae, revealing a genetic separation between these factors and a disconnect between hypersensitivity and neuronal morphology.

The Insulin receptor regulates the persistence of mechanical nociceptive sensitization in flies and mice

This study shows that the insulin receptor regulates persistent mechanical nociceptive sensitization in both flies and mice, independent of metabolic effects.

Pvr and downstream signaling factors are required for spreading of Drosophila hemocytes at larval wound sites

This study identifies Pvr and Pvf1 as essential for hemocyte spreading at Drosophila larval wound sites and identifies downstream factors involved in wound responses.

Injury-induced cold sensitization in Drosophila larvae involves behavioral shifts that require the TRP channels Pkd2 and Brv1.

This study identifies TRP channels Pkd2 and Brv1 as essential for cold sensitization in Drosophila larvae following UV-induced injury, revealing distinct behavioral and neuronal responses.