Developmental BiologyAdvanced SciencePeer-reviewed
Symmetry breaking of hPSCs in micropattern generates a polarized spinal cord-like organoid (pSCO) with dorsoventral organization
Kyubin Seo, Subin Cho, Hyogeun Shin…·Woong Sun
This study generates a polarized spinal cord-like organoid with dorsoventral organization using geometrically confined hPSC cultures and shows that BMP and Shh signaling control DV patterning.
33 citations