Esther Yang

This paper identifies a self-limiting orexin-habenula circuit that promotes stress resilience by modulating dopamine and coping behaviors, and shows that chronic stress disrupts this circuit through epigenetic and inflammatory mechanisms.

This study generates a polarized spinal cord-like organoid with dorsoventral organization using geometrically confined hPSC cultures and shows that BMP and Shh signaling control DV patterning.

This study identifies a novel LHb-RMTg pathway where trace aminergic signalling prevents VTA dopaminergic hypoactivity during acute stress, suggesting TAAR1 as a therapeutic target.

This study investigates the role of SALM1/LRFN2 in synaptic function and behavior by analyzing Lrfn2-/- mice, finding altered synaptic plasticity, inhibitory synapse development, and social communication behaviors.