Author

Jining Huang

California Institute of TechnologyORCID 0000-0002-3798-4790Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:perturbation response prediction· 1 Research Focus:software / tool· 1

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Lisa M. Hochrein· 1 shared Mikhail H. Hanewich-HollatziD· 1 shared Niles A. PierceiD· 1 shared Zhewei CheniD· 1 shared

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2019-2019 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperSynthetic Biology

Lisa M. Hochrein

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1 paper

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Synthetic BiologyACS Central SciencePeer-reviewedJun 4, 2019

Conditional Guide RNAs: Programmable Conditional Regulation of CRISPR/Cas Function in Bacteria via Dynamic RNA Nanotechnology

Mikhail H. Hanewich-Hollatz, Zhewei Chen, Lisa M. Hochrein…·Niles A. Pierce

This paper introduces conditional guide RNAs (cgRNAs) that control CRISPR/Cas activity via RNA triggers, enabling programmable gene regulation in E. coli with varying dynamic ranges and crosstalk levels.

111 citationstop 3%

E. coliCRISPR screen

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