Molecular BiologyPLoS PathogensPeer-reviewed
A single amino acid variant in the variable region I of AAV capsid confers liver detargeting
Ruxiao Xing, Mengyao Xu, Darcy Reil…·Dan Wang
The paper identifies an amino acid variant in AAV capsid VR-1 that reduces liver targeting, suggesting its potential for minimizing liver toxicity in gene therapy.
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