Author

Alessandra Brambati

Memorial Sloan Kettering Cancer CenterORCID 0000-0002-3816-425XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Agnel J. SfeiriD· 2 shared Ahmet DoymaziD· 1 shared Andrea M. GazzoiD· 1 shared Anna Neiman-Golden· 1 shared Benura AzerogluiD· 1 shared Daniel S. HigginsoniD· 1 shared Edaise M. da SilvaiD· 1 shared Fresia G. ParejaiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Agnel J. SfeirORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedMay 10, 2025

RNA Transcripts Serve as a Template for Double-Strand Break Repair in Human Cells

Manisha Jalan, Alessandra Brambati, Hina Shah…·Agnel J. Sfeir

This study demonstrates that RNA transcripts can serve as templates for double-strand break repair in human cells, identifying DNA polymerase-zeta as a key enzyme and revealing genomic scars associated with this process.

12 citations

humanwhole-genome sequencing

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Molecular BiologybioRxivPreprintMar 16, 2023

RHINO restricts MMEJ activity to mitosis

Alessandra Brambati, Olivia Sacco, Sarina Y. Porcella…·Agnel J. Sfeir

This study identifies MMEJ as the primary DSB repair pathway in mitosis and reveals RHINO's role in directing mutagenic repair to M phase.

10 citations

experimental assay

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