Bryan Andrews

The paper uses a deep sequencing assay to analyze how mutations affect circadian clock phenotypes, revealing factorized oscillator properties and mutation-specific effects on period and amplitude.

BCAR improves barcode-sequence mapping by accurately aligning reads and correcting sequencing errors, outperforming existing methods on simulated and experimental data.

This paper introduces a method to detect specific epistasis by analyzing rank statistics in mutagenesis experiments, achieving accuracy comparable to more complex methods.

The paper investigates how phage λ adapts to resistant hosts by analyzing mutational tolerance in its tail fiber protein, identifying variants that confer promiscuity or host-specific infectivity.