Jason D. Goldman

This study shows EBV reprograms B cells in COVID-19 patients, leading to autoimmune-like features such as autoantibodies and dysregulated lipid profiles, similar to lupus and multiple sclerosis.

The paper develops a high-throughput platform to profile antigen-specific CD4+ T cells at single-cell resolution, identifying immunogenic features and functional heterogeneity in viral and cancer contexts.

APMAT analysis links CD8 T cell receptors, cognate antigens, and T cell phenotype/persistence using integrated experimental-computational methods.

This study examines the relationship between T cell receptor (TCR) metrics and COVID-19 disease severity, finding significant associations that vary by TCR subset and collection timing.

This paper benchmarks HLA genotype prediction from single-cell RNA-seq data against molecular genotyping, showing improved accuracy with composite models and meta-analytic approaches.