GenomicsbioRxivPreprint
Single-cell transcriptomic and genomic changes in the aging human brain
Ailsa M. Jeffries, Tianxiong Yu, Jennifer S. Ziegenfuss…·Michael A. Lodato
The paper identifies transcriptomic and genomic changes in the aging human brain using single-nucleus RNA-sequencing and single-cell whole-genome sequencing, revealing age-related gene expression patterns and somatic mutation dynamics.