Author

Yubai Yuan

Pennsylvania State UniversityORCID 0000-0002-3847-2228Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Organism:human· 1

Frequent Co-Authors

Agaz Hussain WaniiD· 2 shared Annie QuiD· 2 shared Derek E. WildmaniD· 2 shared Monica UddiniD· 2 shared Allison E. AielloiD· 1 shared Arlina Shen· 1 shared Chengqi C. Q. WangiD· 1 shared Fei Xue· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioinformatics

Agaz Hussain WaniORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Time-varying mediation analysis for incomplete data with application to DNA methylation study for PTSD

Kecheng Wei, Fei Xue, Qi Xu, Yubai Yuan, Yuexia Zhang, Guoyou Qin, Agaz Hussain Wani, Allison E. Aiello, Derek E. Wildman, Monica Uddin, Annie Qu

The paper develops time-varying mediation analysis methods for DNA methylation data to study dynamic mediation effects of trauma on PTSD using the Detroit Neighborhood Health Study.

The Annals of Applied Statistics · Dec 1, 2025Peer-reviewedBioinformatics

Differentially Expressed Heterogeneous Overdispersion Genes Testing for Count Data

Yubai Yuan, Qi Xu, Agaz Hussain Wani, Jan Dahrendorff, Chengqi C. Q. Wang, Arlina Shen, Janelle Donglasan, Sarah C. Burgan, Zachary Graham, Monica Uddin, Derek E. Wildman, Annie Qu

The paper introduces DEHOGT, a method for detecting differentially expressed genes in RNA-seq data that accounts for overdispersion, and shows it outperforms DESeq and EdgeR on synthetic data and detects more DE genes in microglial cells under stress hormone treatments.

PLoS ONE · Jul 17, 2024Peer-reviewedGenomics