GenomicsPLoS ONEPeer-reviewed
Differentially Expressed Heterogeneous Overdispersion Genes Testing for Count Data
Yubai Yuan, Qi Xu, Agaz Hussain Wani…·Annie Qu
The paper introduces DEHOGT, a method for detecting differentially expressed genes in RNA-seq data that accounts for overdispersion, and shows it outperforms DESeq and EdgeR on synthetic data and detects more DE genes in microglial cells under stress hormone treatments.