Qiang Wang

GGI-RUNNER identifies rare variant gene interactions linked to complex diseases and reveals interconnected gene networks.

The paper identifies PRC1 and CTCF's role in forming chromatin loops that maintain bivalent genes in a poised state for activation during differentiation.

This study identifies shared and distinct genetic loci between bipolar disorder type I and II using integrative genomic analyses, revealing convergence and divergence in their genetic structures.

This paper identifies a common genetic factor across schizophrenia, bipolar disorder, and major depressive disorder using a trans-diagnostic, top-down approach, and links it to ZNF391 expression patterns in the brain that correlate with cognitive and neuroimaging traits.

This study uses two-sample Mendelian randomization to identify cytokines causally linked to schizophrenia and their effects on brain structure and function.