Author
Children's Hospital of PhiladelphiaORCID 0009-0007-6883-0691Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Rahul S. Bhansali, Juan Sebastian Long, Petri Pölönen…·Gerd A. Blobel
The paper identifies LDB1-dependent enhancer connectivity as critical for T-cell leukemia subtypes and reveals a metabolic vulnerability exploitable by statins.
Jessenia Chavez, Trevor Wolf, Cynthia Lascarez-Espana…·Zhonghua Gao
This study identifies POGZ as a novel component of PRC1.6, showing it represses BMP signaling during neuronal differentiation and links to ASD.
Ammar S. Naqvi, Patricia J. Sullivan, Ryan J. Corbett…·Jo Lynne Rokita
The paper analyzes splicing in 729 pediatric brain tumors, identifies splicing-defined subgroups, and highlights CLK1 exon 4 as an oncofetal event linked to tumor prognosis.
Zhuangzhuang Geng, Eric K. Wafula, Ryan J. Corbett…·Jo Lynne Rokita
The paper introduces OpenPedCan, a harmonized multi-omic dataset of pediatric cancer patients, providing integrated genomic, transcriptomic, and proteomic data for research and clinical applications.
Aflah Hanafiah, Zhuangzhuang Geng, Tingting Liu…·Zhonghua Gao
The paper identifies PRC1 and CTCF's role in forming chromatin loops that maintain bivalent genes in a poised state for activation during differentiation.
Jung Kim, Ammar S. Naqvi, Ryan J. Corbett…·Sharon J. Diskin
AutoGVP classifies germline variants using ClinVar and modified InterVar criteria, enabling large-scale variant pathogenicity assessment in research.