Ageing blunts the phospho-proteomic response to resistance exercise in humans
Andrew S. Palmer, Isabelle Alldritt, William Apró, Hannah Huckstep, Oscar Horwath, Lina H.H. Le, Tabitha Cree, Sarah E. Deemer, EL Watson, Richard J. Mills, Sean J. Humphrey, Andrew Philp
This study shows that ageing reduces the phospho-proteomic response to resistance exercise in human skeletal muscle, despite normal mTORC1 activation, suggesting new therapeutic targets for aged muscle.
bioRxiv · Jun 5, 2026 · PreprintPhysiology