Minimally Invasive DNA-Mediated Photostabilization for Extended Single-Molecule and Super-resolution Imaging
Michael Scheckenbach, Cindy M. Close, Julian Bauer, Lennart Grabenhorst, Fiona Cole, Jens Koehler, Siddharth S. Matikonda, Lei Justan Zhang, Thorben Cordes, Martin J. Schnermann, Andreas Herrmann, Philip Tinnefeld, Alan M. Szalai, Viktorija Glembockyte
This paper develops a DNA-mediated photostabilization method for single-molecule and super-resolution imaging, showing improved performance at lower additive concentrations and enabling continuous replenishment of photostabilizers.
bioRxiv · Jan 8, 2025 · PreprintBiophysics