Emma E. Vincent

ABHD11 inhibition drives sterol metabolism to modulate T cell effector function and alleviate autoimmunity

This paper shows that inhibiting ABHD11 reduces T cell cytokine production and alleviates autoimmunity by altering sterol metabolism and LXR activation.

Evaluating the effect of metabolic traits on oral and oropharyngeal cancer risk using Mendelian randomization

This study uses Mendelian randomization to assess the causal effect of obesity and related metabolic traits on oral and oropharyngeal cancer risk, finding limited evidence of a direct causal link.

Investigating the effect of sexual behaviour on oropharyngeal cancer risk: a methodological assessment of Mendelian randomization

This study uses Mendelian randomization to assess the causal effect of sexual behavior on oropharyngeal cancer risk, finding attenuated associations after adjusting for confounders.

A framework for research into continental ancestry groups of the UK Biobank

The paper describes the continental ancestry and population structure of non-white British individuals in the UK Biobank using reference populations and clustering methods.

Early metabolic features of genetic liability to type 2 diabetes: cohort study with repeated metabolomics across early life

This study identifies early metabolic features associated with genetic liability to type 2 diabetes across childhood, adolescence, and young adulthood using longitudinal metabolomics data.

MELODI - Mining Enriched Literature Objects to Derive Intermediates

MELODI identifies mechanistic pathways between biomedical concepts by mining literature, generating hypotheses for further investigation.