Differentiation of naive into memory-phenotype CD8+ T cells does not promote the breakdown of peripheral tolerance in irradiated mice
Marine Villard, Gabriel Espinosa-Carrasco, Javier Hernández
This study shows that lymphopenia-induced proliferation and differentiation of naive CD8+ T cells into memory-like cells do not prevent cross-tolerance breakdown in irradiated mice.
bioRxiv · Sep 8, 2025 · PreprintImmunology