Author
Montreal Neurological Institute and HospitalORCID 0000-0002-3906-5616Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Jack Lam, Nicolás von Ellenrieder, Meriem Hamel…·Roy Dudley
The paper examines histopathology in FDG-PET hypometabolic regions of pediatric epilepsy patients with FCD type II, finding fFCD concentrated at the lesion epicenter and DNO present in both epicenter and hypometabolic borders.
Justin Simo, Alexandre Janer, Hana Antonická…·Roberta La Piana
This paper identifies bi-allelic AMPD2 variants as a cause of Leigh syndrome, showing they lead to complex V assembly defects and cytosolic purine imbalance.
Carol X.‐Q. Chen, Zhipeng You, Narges Abdian…·Thomas M. Durcan
The paper generates PRKN and PINK1-KO and double KO human iPSC lines using CRISPR/Cas9 to model Parkinson's disease.
Nguyen‐Vi Mohamed, Julien Sirois, Janani Ramamurthy…·Thomas M. Durcan
This study uses midbrain organoids from SNCA triplication patients to model synucleinopathy features, showing increased alpha-synuclein expression and aggregation linked to dopaminergic neuron loss.