Roy Dudley

The paper examines histopathology in FDG-PET hypometabolic regions of pediatric epilepsy patients with FCD type II, finding fFCD concentrated at the lesion epicenter and DNO present in both epicenter and hypometabolic borders.

The paper identifies a reproducible functional connectivity signature in temporal lobe epilepsy through a large-scale connectome-wide analysis.

This study shows fibrinogen has opposing effects on human oligodendrocyte lineage cells depending on their maturation stage, inhibiting early differentiation but enhancing myelination in mature cells.

This study identifies four distinct HRF shape groups in the epileptic brain, showing HRF variability is linked to both anatomical location and pathology.

This paper reviews AI/ML applications in MRI for epilepsy, finding high accuracy in diagnosis and prediction but significant bias issues limiting clinical use.

The paper investigates how epigenomic factors like chromatin accessibility and histone modifications affect human oligodendrocyte myelination and age-related vulnerability to injury.

This study investigates cerebral perfusion changes in temporal lobe epilepsy using multimodal imaging and finds widespread CBF reductions linked to structural and network disruptions.

The paper optimizes an iMGL protocol to generate microglia-like cells from an ALSP patient, revealing functional defects in migration and phagocytosis.

The paper compares culture media effects on human microglia, finding that serum supports key genes and phagocytic function, while CSF1R signaling reliance decreases in culture.