Analysis of genomic DNA methylation and gene transcription modulation induced by DNMT3A deficiency in HEK293 cells
Mengxiao Zhang, Jiaxian Wang, Qiuxiang Tian, Lei Feng, Hui Yang, Nan Zhu, Xingchen Pan, Jianwei Zhu, Peng Chen, Huili Lu
This study investigates the effects of DNMT3A deficiency on DNA methylation and gene expression in HEK293 cells, revealing reduced methylation and altered gene regulation.
bioRxiv · Jul 11, 2020 · PreprintMolecular Biology