Peng Chen

Tcf12 controls dynamic calvarial bone growth and motor learning in mice

This study investigates the role of Tcf12 in calvarial bone development and motor learning in mice, finding that Tcf12 loss leads to altered bone formation and impaired motor learning.

De novo genome assemblies from two Indigenous Americans from Arizona identify new polymorphisms in non-reference sequences

This study generates de novo genome assemblies from two Indigenous Americans, identifies non-reference sequences, and shows they improve variant detection in underrepresented populations.

Habitual Coffee Consumption Increases Risks for Metabolic Diseases: Genome-wide Association Studies and a Phenotype-wide Two Sample Mendelian Randomization Analysis

This study identifies genetic loci associated with coffee consumption and finds that coffee increases risks for metabolic diseases through Mendelian randomization analysis.

Analysis of genomic DNA methylation and gene transcription modulation induced by DNMT3A deficiency in HEK293 cells

This study investigates the effects of DNMT3A deficiency on DNA methylation and gene expression in HEK293 cells, revealing reduced methylation and altered gene regulation.