Author

Lei Feng

National University of Singapore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Genomics· 2 Bioinformatics· 1 Molecular Biology· 1 Neuroscience· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Organism:human· 2 Organism:Arabidopsis· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Aarthi RavikrishnaniD· 1 shared Ahmad Nazri Mohamed Naim· 1 shared Amanda Hui Qi NgiD· 1 shared Andrea Britta MaieriD· 1 shared Anis LarbiiD· 1 shared Baosen GuoiD· 1 shared Binghang LiuiD· 1 shared Blake C. MeyersiD· 1 shared

Activity by Year

2020-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperGenomics

Aarthi RavikrishnanORCID

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6 papers

Recent·Most cited

Biomolecular condensation of ERC1 recruits ATG8 and NBR1 to drive autophagosome formation for plant heat tolerance

Ka Kit Chung, Kai Ching Law, Ziwei Zhao, Juncai Ma, Xiao-Tong Zhan, Cheuk Him Chiang, Kwan Ho Leung, Ruben Shrestha, Yixin Wu, Chaorui Li, Ka Ming Lee, Lei Feng, Xibao Li, Kam‐Bo Wong, Shou‐Ling Xu, , Xiaohong Zhuang

This study identifies ERC1 as a protein that forms biomolecular condensates to recruit ATG8 and NBR1, promoting autophagosome formation and enhancing heat tolerance in Arabidopsis.

Proceedings of the National Academy of Sciences · Nov 10, 2025Peer-reviewedPlant Biology

Gut metagenomes of Asian octogenarians reveal metabolic potential expansion and distinct microbial species associated with aging phenotypes

Aarthi Ravikrishnan, Indrik Wijaya, Eileen Png, Kern Rei Chng, Eliza Xin Pei Ho, Amanda Hui Qi Ng, Ahmad Nazri Mohamed Naim, Jean-Sébastien Gounot, Shou Ping Guan, Jasinda H. Lee, Lihuan Guan, Chenhao Li, Jia Yu Koh, Paola Flórez de Sessions, Woon‐Puay Koh, , Niranjan Nagarajan

The paper analyzes gut metagenomes of Asian octogenarians to identify age-related microbial shifts and their associations with aging phenotypes.

Nature Communications · Sep 5, 2024Peer-reviewedGenomics

sRNAanno --- a database repository of uniformly-annotated small RNAs in plants

Chengjie Chen, Jiawei Li, Junting Feng, Bo Liu, Lei Feng, Xiaoling Yu, Guanliang Li, Jixian Zhai, Blake C. Meyers, Rui Xia

sRNAanno provides a comprehensive database of uniformly-annotated small RNAs in 138 plant species, including miRNAs, phasiRNAs, and hc-siRNAs, along with a visualization tool for NGS sRNA data.

Horticulture Research · Feb 28, 2021Peer-reviewedGenomics

Key Nucleation Stages and Associated Molecular Determinants and Processes in pH-Induced Formation of Amyloid Beta Oligomers as Revealed by High-Speed AFM

Lei Feng, Hiroki Watanabe, Paul J. Molino, Gordon G. Wallace, Son Lam Phung, Takayuki Uchihashi, Michael J. Higgins

This study uses high-speed AFM to visualize pH-induced AB42 peptide nucleation and identifies key molecular stages in oligomer formation.

bioRxiv · Oct 17, 2020 · PreprintNeuroscience

Analysis of genomic DNA methylation and gene transcription modulation induced by DNMT3A deficiency in HEK293 cells

Mengxiao Zhang, Jiaxian Wang, Qiuxiang Tian, Lei Feng, Hui Yang, Nan Zhu, Xingchen Pan, Jianwei Zhu, Peng Chen, Huili Lu

This study investigates the effects of DNMT3A deficiency on DNA methylation and gene expression in HEK293 cells, revealing reduced methylation and altered gene regulation.

bioRxiv · Jul 11, 2020 · PreprintMolecular Biology

A Reference Feature based method for Quantification and Identification of LC-MS based untargeted metabolomics

enhui luan, Ken Cheng, Qiaoyun Long, Dehua Li, Zhenyu Li, Binghang Liu, Yalan Wang, Wei Li, Baosen Guo, Fengji Tan, Xiaoyi Yi, Lei Feng, Jiaping Song, Hancheng Zheng

This paper introduces RFQI, a reference-feature based method for quantification and identification in LC-MS untargeted metabolomics, improving batch consistency and metabolite detection efficiency.

bioRxiv · Mar 26, 2020 · PreprintBioinformatics