Author
National Institutes of HealthORCID 0000-0002-3926-5503Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Samuel Crofts, Caleb M. Grenko, Neil A. Robertson…·Tamir Chandra
The paper develops COMET, a method to infer clonal hematopoiesis from bulk DNA methylation data, showing it accurately detects clonal expansion and replicates known genetic associations.
Caleb M. Grenko, Henry J. Taylor, Lori L. Bonnycastle…·D. Leland Taylor
This study uses single-cell RNA sequencing to analyze gene expression changes in human pancreatic islets under different glucose conditions over 24 hours, identifying genes and modules associated with time, glucose exposure, and their interaction.
Dongxiang Xue, Narisu Narisu, D. Leland Taylor…·Francis S. Collins
This study functionally interrogates 20 T2D-associated genes using isogenic hESC-derived β-like cells, identifying variants and genes linked to insulin production and lipotoxicity sensitivity.
Henry J. Taylor, Yu-Han Hung, Narisu Narisu…·D. Leland Taylor
This paper identifies miRNAs associated with type 2 diabetes and glycemic traits through genetic analysis of miRNA expression in human pancreatic islets.