Author

Joseph R. Palmeri

Koch Institute for Integrative Cancer Research At MITORCID 0000-0002-3932-9124Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Anna M. RomanoviD· 1 shared Darrell J. IrvineiD· 1 shared Elizabeth FinkiD· 1 shared Jordan A. StinsoniD· 1 shared Karl Dane WittrupiD· 1 shared Lauren DuhameliD· 1 shared Luciano SantollaniiD· 1 shared Owen T. PorthiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Anna M. RomanovORCID

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1 paper

Recent·Most cited

CD45 sequestration lowers the signaling threshold in lymphocytes and enhances anti-tumor immunity

Lauren Duhamel, Yiming J. Zhang, William Pinney, Elizabeth Fink, Qingyang Henry Zhao, Anna M. Romanov, Jordan A. Stinson, Luciano Santollani, Joseph R. Palmeri, Owen T. Porth, Darrell J. Irvine, Karl Dane Wittrup

This study shows that CD45 sequestration lowers T cell activation thresholds and enhances anti-tumor immunity when combined with IL-12 therapy in mouse models.

bioRxiv · Jul 29, 2025 · PreprintImmunology