Author

Murielle Saade

Consejo Superior de Investigaciones CientíficasORCID 0000-0002-3937-4291Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Organism:mouse· 1

Frequent Co-Authors

Naiara AkizuiD· 2 shared Paula Espana-BonillaiD· 2 shared Adam JacksoniD· 1 shared Alexander M. HoltziD· 1 shared Anna ChasseventiD· 1 shared Anna HurstiD· 1 shared Axelle WilmerdingiD· 1 shared Carolina Gracia-DiaziD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Naiara AkizuORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintDec 12, 2025

Rootletin Fiber Dynamics Integrate Cytoskeletal Programs to Shape Neuroepithelial Architecture

Axelle Wilmerding, Glòria Casas Gimeno, Paula Espana-Bonilla…·Murielle Saade

This study reveals Rootletin's dynamic role in neuroepithelial cell morphogenesis and shows its aberrant interaction with Zika virus NS5 protein, linking infection to premature delamination.

DOI 10.64898/2025.12.09.693208

mouseexperimental assay

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Genetic & Genomic MedicinemedRxivPreprintAug 9, 2022

Gain and loss of function variants in EZH1 disrupt neurogenesis timing and cause overlapping neurodevelopmental disorders

Carolina Gracia-Diaz, Yijing Zhou, Qian Yang…·Naiara Akizu

1 citation

humanexperimental assay

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Developmental BiologyCell stem cellPeer-reviewedNov 3, 2020

Multimerization of Zika Virus-NS5 causes a ciliopathy and forces premature neurogenesis

Murielle Saade, Diego S. Ferrero, José Blanco-Ameijeiras…·Elisa Martı́

This study shows that ZikV-NS5 multimerization causes a ciliopathy and premature neurogenesis in neural progenitor cells, identifying potential therapeutic targets for congenital Zika syndrome.

43 citations

humanexperimental assay

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