How human-derived brain organoids are built differently from brain organoids derived of genetically-close relatives: A multi-scale hypothesis
Tao Zhang, Sarthak Gupta, Madeline A. Lancaster, Jennifer M. Schwarz
The paper proposes a multiscale hypothesis to explain structural differences in brain organoids derived from human versus genetically close non-human primate stem cells, linking chromatin reorganization to delayed cell fate transitions.
Soft Matter · Jan 1, 2026Peer-reviewedDevelopmental Biology