Vimentin promotes collective cell migration through collagen networks via increased matrix remodeling and spheroid fluidity
Minh Tri Ho Thanh, Arun Poudel, Shabeeb Ameen…·Alison E. Patteson
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Indian Creek FarmORCID 0000-0001-9880-9999Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Minh Tri Ho Thanh, Arun Poudel, Shabeeb Ameen…·Alison E. Patteson
Tao Zhang, Sarthak Gupta, Madeline A. Lancaster, Jennifer M. Schwarz
The paper proposes a multiscale hypothesis to explain structural differences in brain organoids derived from human versus genetically close non-human primate stem cells, linking chromatin reorganization to delayed cell fate transitions.
Ligesh Theeyancheri, Edward J. Banigan, Jennifer M. Schwarz
The paper models nuclear chromatin compartmentalization using crosslinking, contractile motors, and deformable lamina, showing how these factors drive genomic segregation and heterochromatin formation.
Andrew K. Lawton, Tyler Engstrom, Daniel J. Rohrbach…·Alexandra L. Joyner
The paper shows cerebellar folding arises from mechanical forces due to uniform cell behavior, not a cellular pre-pattern.