Molecular BiologybioRxivPreprint
A programmable pAgo nuclease with RNA target preference from the psychrotolerant bacteria Mucilaginibacter paludis
Wenqiang Li, Yang Liu, Fei Wang, Lixin Ma
The paper characterizes MbpAgo, a pAgo from Mucilaginibacter paludis that preferentially cleaves RNA over DNA, and demonstrates its temperature tolerance and guide flexibility.
DOI 10.1101/2021.06.08.447469