Author

Xi Chen

University of Southern CaliforniaORCID 0000-0002-3958-6905Unclaimed ORCID profile · follow to get notified of new preprints

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Xi Chen12 papers · AstraZeneca (United States)

Biology Disciplines

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron Clifford BrowniD· 1 shared Albert Kim· 1 shared Andrew P. McMahoniD· 1 shared Andrew Ransick· 1 shared Bin LiiD· 1 shared Bing ReniD· 1 shared Helena BugacoviD· 1 shared Leif H. OxburghiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperDevelopmental Biology

Aaron Clifford BrownORCID

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1 paper

Recent·Most cited

A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells

Qiuyu Guo, Albert Kim, Bin Li, Andrew Ransick, Helena Bugacov, Xi Chen, Nils O. Lindström, Aaron Clifford Brown, Leif H. Oxburgh, Bing Ren, Andrew P. McMahon

The paper shows that β-catenin modulates TCF/LEF binding at gene targets, switching from inhibitory to activating complexes during nephron progenitor cell differentiation.

eLife · Feb 15, 2021Peer-reviewedDevelopmental Biology