GeneticsbioRxivPreprint
Retinal pigment epithelium-derived PD-L1 reprograms microglial cells and protects against retinal degeneration in mouse models of experimental AMD and genetic retinitis pigmentosa
Zhongyuan Su, Jing Wang, Qinghua Lai…·Ling Hou
This study shows that PD-L1 from retinal pigment epithelium reprograms microglia to reduce inflammation and protect against retinal degeneration in mouse models.
DOI 10.1101/2025.07.26.666839