A Fluorescent Split Aptamer for Visualizing RNA-RNA Assembly In Vivo
Khalid K. Alam, Kwaku D. Tawiah, Matthew F. Lichte, David Porciani, Donald H. Burke
This paper introduces a split-aptamer system called Split-Broccoli that enables visualization of RNA-RNA assembly in vivo through fluorescence activation upon hybridization of two RNA strands.
ACS Synthetic Biology · May 26, 2017Peer-reviewedSynthetic Biology